San Francisco
Out: WR Braylon Edwards (knee), FB Moran Norris (fibula), CB Tramaine Brock (hand)
Probable: LB NaVorro Bowman (neck), WR Michael Crabtree (feet), WR Ted Ginn (finger), S Dashon Goldson (knee), G Mike Iupati (knee), NT Isaac Sopoaga (infection), OL Adam Snyder (forearm), CB Shawntae Spencer (toe)
Detroit
Out: LB Justin Durant (concussion), S Vincent Fuller (elbow), TE Tony Scheffler (concussion)
Questionable: CB Aaron Berry (groin), WR Rashied Davis (foot), T Jason Fox (foot), S Amari Spievey (hamstring)
Probable: DE Cliff Avril (elbow), S Louis Delmas (abdomen), LB Doug Hogue (hamstring),DE Lawrence Jackson (hamstring), LB DeAndre Levy (knee), LB Stephen Tulloch (ankle)